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Lymphoma is one of the most common cancers in dogs, and while it can often be managed with treatments like chemotherapy, there comes a point where the disease may progress despite interventions. Recognizing the signs that your dog is nearing the end of their journey can help you provide comfort and make informed decisions about their care. Here\u2019s a guide to understanding the signs of late-stage lymphoma and how to support your beloved pet during this difficult time. Understanding Canine LymphomaLymphoma affects the lymphatic system, which is part of the immune system. It can manifest in different parts of the body, including the lymph nodes, spleen, liver, and gastrointestinal tract. 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