Over the years I have seen many dogs with anal sac cancer, and it is one of those tumors that always stays in the back of my mind. Not because it is rare, but because it is so easy to miss in the beginning. So many owners tell me the same thing afterward. Looking back, the signs were already there. They just did not think it could be cancer. In the beginning, the changes are usually very small. A dog may start taking longer to poop. They may squat for a long time and sometimes cry or strain. They used to go every day and now it is every two or three days. Sometimes they are constipated, sometimes the stool is soft. Most people think it is just age or maybe diet. But in reality, a tumor may already be slowly pressing against the rectum. Later you may notice a small lump on one side of the anus. It feels firm and does not move much. Your dog may start scooting more or licking the area more often. They may look uncomfortable when sitting. Many people think it is just an anal gland problem. But early anal sac cancer can look exactly the same. As time goes on, walking and stamina often change too. The back legs seem weaker. Stairs become harder. Walks become shorter. They sit down more often and take longer to stand up. It is easy to think this is just arthritis. Sometimes it is actually the tumor taking up space inside the pelvis. One important sign many people miss is drinking much more water. Some dogs suddenly drink a lot. They need to urinate more often. They may wake you up at night to go outside. Some even start having accidents. This is often caused by high calcium levels from the tumor, which can damage the kidneys and heart over time. In later stages, the whole dog seems to change. They lose their appetite. They lose weight. They have less energy. They get tired easily. Their breathing becomes faster. Some start coughing if the cancer has spread to the lungs. Many owners say He suddenly aged overnight But it is not aging. It is the cancer affecting the whole body. If your dog is over eight years old and you notice even a few of these changes, it is worth getting them checked. A simple ultrasound and a small needle biopsy can sometimes give you six months or even a year of earlier detection. And that time can make a huge difference. Anal sac cancer does not appear overnight. It grows quietly and slowly and then one day it becomes impossible to ignore. The regret is never checking too early. The regret is always finding out too late. So next time you are bathing or brushing your dog, take a moment to feel around the anus. Watch how they walk. Notice the small changes. Sometimes that small moment can buy you much more time together. And time is everything. — Recently, we also received an inquiry from a client in Germany. Their dog has been diagnosed with anal sac carcinoma and is currently on a long-term management plan. The dog is receiving Palladia every other day, and Metacam on the alternate days for pain and inflammation control. The family wanted to know if there was anything more they could do to improve their dog’s quality of life and hopefully extend their time together. Our professional response was as follows. Palladia is not a miracle drug for anal sac carcinoma. Based on clinical data, only about 40 to 60 percent of dogs respond to Palladia. Its main role is to control tumor growth, slow disease progression, and in some cases reduce tumor size. It is not a curative treatment. Metacam should be given on a regular schedule. Since the current pain and anti-inflammatory control is effective, there is no need to change medications at this time. If reduced effect develops in the future, alternative pain management options can be considered then. In addition, we recommended adding TCMVET Baituxiao as part of a systemic tumor management program. This formula works on the whole body and can help reduce tumor burden, decrease complications, relieve discomfort, and provide long-term support. When using Baituxiao, there is no need to add other herbal or mushroom supplements, as the formulation is already comprehensive. Palladia, Meloxicam, and TCMVET Baituxiao can be used together as an integrated long-term management approach. Based on our clinical experience, with consistent use over time, many dogs show stable and positive results. We also asked about the dog’s body weight so that we could calculate the appropriate dosage and design a more precise long-term management plan.