Below are the literature for several of these herbs; more relevant literature is available on the purchase page for your reference. Baituxiao is made up of many herbs and mushrooms, and it is multi-faceted; it will definitely help your pet.
Hedyotis diffusa Willd (HDW):
A systematic review of bioactive constituents and underlying molecular mechanisms of HDW was published in Biomedicine & Pharmacotherapy Volume 130, October 2020. The review discussed a total of 58 different kinds of active antitumor components isolated, fridofluids from ding idofluvoids, incid onol glycosides, anthraquinones , phenolic acids, and their derivatives, sterols, and volatile oils. Their antitumor activities include inhibition of tumor cell proliferation, induction of tumor cell apoptosis and tumor angiogenesis, regulation of the host immune response, anti-inflammatory and antioxidant.
Antitumor potential of Hedyotis diffusa Willd: A systematic review of bioactive constituents and underlying molecular mechanisms DOI:10.1016/j.biopha.2020.110735
The Hedyotis diffusa Willd. (Rubiaceae): A Review on Phytochemistry, Pharmacology, Quality Control and Pharmacokinetics DOI: 10.3390/molecules21060710
Arnebia euchroma (Royle) Johnst:
It has chemical components such as naphthoquinones, alkannins, shikonins, and their derivatives, which have widespread biological properties including wound healing, antibacterial, antifungal, antiviral, and anti-inflammatory . And induce apoptosis to play an anti-tumor effect.
A network pharmacology approach study found that Arnebia euchroma candidate targets were significantly associated with several apoptosis and inflammation-related biological pathways, such as MAPK signaling, PI3K-Akt signaling, IL-17 signaling, and T cell signallingtor.
In vitro and in vivo antitumor effects of acetylshikonin isolated from Arnebia euchroma (Royle) Johnst (Ruanzicao) cell suspension cultures DOI:10.1186/1749-8546-4-14
Insights into the mechanism of Arnebia euchroma on leukemia via network pharmacology approach DOI: 10.1186/s12906-020-03106-z
Bulbus Fritillariae Thunbergii (BFT), also known as Fritillaria thunbergii(Zhe Beimu). The bulbs are thought to act specifically on tumors and swellings of the throat, neck and chest, and they are used in the treatment of nodules, scrofula, abscesses and boils, and breast cancer etc.
Fritillariae Thunbergii Bulbus: Traditional Uses, Phytochemistry, Pharmacodynamics, Pharmacokinetics and Toxicity DOI: 10.3390/ijms20071667
Fritillaria thunbergii Miq. (Zhe Beimu): A review on its traditional uses, phytochemical profile and pharmacological properties DOI: 10.1016/j.fct.2021.112289
has been shown to have a wide assortment of therapeutic applications for animals, including the treatment of irregular weight loss due to cancer. It induces cell differentiation, reduces the effects of chemical carcinogens, mitigates inflammatory carcinogenesis, induces apoptosis, inhibits proliferation.
Veterinary Herbal Medicine: A Systems-Based Approach DOI: 10.1016/B978-0-323-02998-8.50024-X
Efficacy and safety of ginseng DOI: 10.1017/s1368980000000550
has been shown to have anti-tumor effects, mainly because of two important components in the mushroom: triterpenes and polysaccharides. Studies have shown that Reishi can inhibit tumor growth by 88% or more, depending on the case. In some animals involved in the study, the tumor disappeared completely. Even when Reishi does not completely eliminate tumors, it still prevents them from growing.It is believed to modulate many components of the immune system such as antigen-presenting cells, NK cells, T and B lymphocytes.
Ganoderma lucidum (Reishi mushroom) for cancer treatment DOI: 10.1002/14651858.CD007731.pub3
Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities DOI: 10.1142/S0192415X11008610
Turkey tail mushroom (turkey tail):
Turkey tail mushroom contains beta-glucan polysaccharides, which are thought to stimulate natural killer cells, boosting your dog’s immunity and healing abilities. A study published in Evidence-Based Complementary Medicine looked at the effectiveness of turkey tail mushrooms in dorms emangiosarcoma is a form of vascular cancer that spreads quickly (spreading to other parts of the body). It’s a highly aggressive condition that’s mostly found in a dog’s spleen.
Guggenheim AG, Wright KM, Zwickey HL. Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology. Integr Med (Encinitas). 2014 Feb;13(1):32-44. PMID: 26770080; PMCID: PMC4684115.
PDQ Integrative, Alternative, and Complementary Therapies Editorial Board. Medicinal Mushrooms (PDQ®): Patient Version. 2022 Jul 29. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK424937/
Phytochemistry of Prunella vulgaris (PV) revealed diverse metabolites such as triterpenoids, phenolic acids, sterols, carbohydrates, coumarins, fatty acids, and volatile oils. Many of these compounds have been found to possess a wide range of biological activities themselves, including antimicrobial, immunosuppressive, anticancer, cardioprotective, antiallergic and anti-inflammatory activities.
Prunella vulgaris: A Comprehensive Review of Chemical Constituents, Pharmacological Actions, and Clinical Applications DOI: 10.2174/1381612825666190313121608
Prunella vulgaris L: Key pharmacology, explanatory traditional uses, and broad phytochemistry: a review DOI: 10.2174/1570163818666210203181542
Tienchi Ginseng（Panax notoginseng）：
More than 200 chemical components were isolated from Panax notoginseng, including saponins, polysaccharides, dianthus, amino acids, flavonoids, phytosterols, cyclic peptides, sugars, fatty acids, volatile oils, aliphatic acetylenes, and trace elements. Has multiple effects, hemostatic and wound healing activity, antioxidant activity, anti-inflammatory activity, hypoglycemic and anti-hyperlipidemic activity, anticoagulant activity, neuroprotective effect, hepatoprotective effect, renal protective effect, anti-tumor activity, anti-vascular senescence.
Therapeutic Potential and Cellular Mechanisms of Panax Notoginseng on Prevention of Aging and Cell Senescence-Associated Diseases DOI: 10.14336/AD.2017.0724
I have a tumor on my dog’s liver and surgery could be very risky; I don’t know what to do. After using it on dogs for a period of time, it was found through subsequent examinations that it had indeed inhibited; the tumor developed slower than expected, and did not deteriorate rapidly. Thanks for this herb.
It is a breast tumor that has recurred many times; this is a picture of the most serious time; ulceration has occurred. Veterinarians don’t have a good idea either. Insist on using it for dogs and it is now under control. I trust Baituxiao to help my dog all the time.
The vet helped my dog get rid of some of the skin tumors, but then a lot grew; I don’t know how to get rid of it completely. I chose this herb to help it get under control and nothing new has come up in recent times; I am very satisfied.
My avatar is the cytology of a dog with a mast cell tumor.I am a veterinarian and I came across this supplement through a recommendation from a Chinese herbalist; I tried it and it helped my dog; it has a wide range of applications; it always surprises my clients.
My puppy has a small tumor; he has recovered. It was swollen at first, and it was firm to the touch; it gradually became soft after a period of time, and it was not so firm; then it gradually shrunk.
Our vet said our dog had only a few days to live, long ago! She gave us a few capsules and another patient said it worked so we gave it a try. We appreciate all of this “extra” time with our girls. Also, she is totally herself and doesn’t look frail or sick. I have now ordered 10 more bottles! When in doubt, try it! I appreciate it!
Help it with TCMVET Baituxiao
The plant formula ingredients of TCMVET Baituxiao are very scientific and comprehensive. For more literature, see our blog and product detail pages.